Diabetic ketoacidosis and prolonged hyperchloraemic acidosis in a patient treated with risperidone
نویسندگان
چکیده
Diabetic ketoacidosis (DKA) is a life-threatening complication of diabetes. The development of metabolic syndrome is widely recognised with the use of atypical antipsychotic agents, and not infrequently DKA has been described with some of these drugs. We describe a complex patient with HIV who presented with severe DKA and prolonged hyperchloraemic acidosis, which we postulate was associated with risperidone therapy.
منابع مشابه
Management of diabetic ketoacidosis
Although the mortality of diabetic ketoacidosis (DKA) has decreased substantially in the developed world, high mortality rates still prevail in South Africa, thus making this an important condition to recognise early and manage well. This review discusses the treatment of DKA, with emphasis on the controversial aspect of initial fluid replacement therapy. Current guidelines recommend the use of...
متن کاملEuglycemic Diabetic Ketoacidosis in a 27 year-old female patient with type-1-Diabetes treated with sodium-glucose cotransporter-2 (SGLT2) inhibitor Canagliflozin
We are reporting a timely case of atypical euglycemic diabetic ketoacidosis in a type 1 diabetic patient treated with sodium-glucose cotransporter-2 (SGLT-2) inhibitor canagliflozin. The clinical history, physical examination findings and laboratory values are described. Other causes of acidosis such as salicylate toxicity or alcohol intoxication were excluded. Ketoacidosis resolved after incre...
متن کاملVARIATIONS OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE ACTIVITY IN VARIOUS TISSUES INDUCED BY METABOLIC ALKALOSIS, ACIDOSIS AND DIABETES
The effects of chronic metabolic acidosis, alkalosis and alloxan-induced ketoacidosis on G6PD activity of rat kidney, liver and erythrocytes were studied. Metabolic acidosis significantly increased the activity of kidney enzyme (55%) but decreased the liver (43%) and erythrocyte (38%) enzyme activities. Alkalosis did not make a significant change in the kidney or liver enzyme activity but ...
متن کاملEuglycemic Diabetic Ketoacidosis in a Patient with Type II Diabetes Mellitus, Ascites and Poor Nutrition on SGLT2 Inhibitor
Title: This is the case of a patient with Euglycemic Diabetic Ketoacidosis (euDKA), ascites, poor nutrition and diabetes mellitus type II on SGLT2 inhibitor. Background: euDKA is an under-reported and under-diagnosed condition that mainly occurs in type I diabetes mellitus patients and in patients with prolonged starvation. The aim of this report is to shed the light on an additional risk facto...
متن کاملAtypical diabetic ketoacidosis: case report.
BACKGROUND Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus and can lead to death if untreated. It is a complex metabolic state characterised by hyperglycaemia, acidosis and ketonuria. Bonsai is one of the herbal incense products that contains synthetic cannabinoid and can be easily accessible via the internet in many countries. It cannot be detect...
متن کامل